Futbolistas Ecuatorianos que Jugaron en MLS
| JUGADOR | EQUIPO | AÑOS |
| Eduardo Hurtado | L.A. Galaxy | 1996-97 |
| NY Metrostars | 1998-99 | |
| NE Revolution | 2000 | |
| Ariel Graziani* | NE Revolution | 2000 |
| Dallas Burn | 2000-02 | |
| San Jose Earthquakes | 2002 | |
| Peter Villegas | NY Metrostars | 1999-2000 |
| DC. United | 2003 | |
| Wellington Sanchez | NY Metrostars | 1998 |
| LA Galaxy | 1999 | |
| Martin Klinger | LA Galaxy | 2001-02 |
| Fausto Klinger | LA Galaxy | 2001 2002 |
| Roberto Mina | Dallas Burn | 2005-07 |
| Joao Plata | Toronto FC | 2011 |
| Real Salt Lake City | 2013- | |
| Victor Estupiñan | Chivas USA | 2011 |
| Edmundo Zura | San Jose | 2011 |
| Geovanni Caicedo | Toronto FC | 2012 |
| Miller Bolaños | Chivas USA | 2012 |
| Oswaldo Minda | Chivas USA | 2012- |
| Diego Calderon | Colorado Rapids | 2013 |
| Claudio Bieler* | Kansas City Sporting | 2013- |
| Juan Luis Anangono | Chicago Fire | 2013- |
| Felix Borja | Chivas USA | 2014- |
| Luis Bolaños | Chivas USA | 2014- |
| Andres Mendoza | New York City FC | 2015 |
| Carlos Gruezo | FC Dallas , San Jose Earthquakes. | 2016, 2023. |
| Anibal Chala | FC Dallas | 2017- |
| Cristian Penilla | New England Revolution | 2018- |
| Romario Ibarra | Minnesota United | 2018 |
| Jhegson Mendez | Orlando City | 2019 |
| Xavier Arreaga | Seattle Sounders | 2019 |
| Diego Palacios | LAFC | 2019 |
| José Cifuentes | LAFC, Toronto FC | 2020-23, 2025- |
| Alexander Alvarado | Orlando City | 2020 |
| John Espinoza | Chicago Fire | 2021 |
| Anderson Julio | Real Salt Lake City, Dallas FC | 2021-24, 2025- |
| Gustavo Vallecilla | FC Cincinnati, Colorado Rapids | 2021- |
| Michael Estrada | DC United | 2022 |
| Jordy Alcivar | Charlotte FC | 2022 |
| Allan Franco | Charlotte FC | 2022 |
| Pedro Vite | Vancouver Whitecaps | 2022 |
| Luis F. Fernandez Salvador | Vancouver Whitecaps | 2022 |
| Leonardo Campana | Miami Inter, New England Revolution | 2022-2024, 2025- |
| Washington Corozo | Austin | 2022 |
| Josue Quiñonez | Dallas FC | 2022 |
| Marco Angulo | Cinicinnati FC | 2023 |
| Dixon Arroyo | Miami Inter | 2023 |
| Jefferson Valverde | Houston Dynamo | 2024 |
| Patricson Delgado | Dallas FC | 2024- |
| Joao Ortiz | Portland Timbers | 2025 |
| Allen Obando | Inter Miami | 2025 |
| Bryan Ramirez | Cincinnati FC | 2026 |
| Bruno Caicedo | Vancouver Whitecaps | 2026 |
| *Argentino nacionalizado Ecuatoriano. |
